REthinking Clinical Trials



Magnesium replacement strategies for patients receiving palliative-intent treatment with Cisplatin, Carboplatin, Panitumumab or Cetuximab 

Principal Investigator(s): Dr. Michael Vickers NCT02690012
Hypomagnesemia is a common consequence of many anti-cancer therapies. However optimal replacement strategies are unknown. The trial assessed the feasibility of comparing the benefits of treating hypomagnesemia to magnesium oxide or magnesium citrate in patients receiving palliative treatment with cisplatin, carboplatin, Panitumumab or Cetuximab. This study has been completed.

Sites: The Ottawa Hospital

Tags: Palliative chemotherapy


  • A comparison of oral magnesium supplements for cancer treatment-induced hypomagnesemia: results from a pilot randomized trial. Vickers et al. 2021. In press.

A Prospective Multi-Centre, Randomized Study Comparing the Addition of Tapering Dexamethasone to other Standard of Care Therapies for Taxane- Associated Pain Syndrome (TAPS) in breast cancer patients Supportive Care in Cancer. Clemons et al, 2021. In press