REthinking Clinical Trials

REaCT-Hot Flashes Project

REaCT-Hot Flashes Project

Project for patient survey for patients with early stage breast cancer, that have experienced hot flashes.

Principal Investigator(s): Dr. Sharon McGee Not applicable
REaCT-Hot Flashes is a study investigating treatment-related, vasomotor symptoms, in patients with early-stage breast cancer. These symptoms include hot flashes, and sweats, and can occur due to the impacts of chemotherapy, and/or endocrine therapy, on estrogen levels in the body. These symptoms can negatively impact patient quality of life and impair treatment compliance. The goal of this study is to increase our understanding of vasomotor symptoms to help design randomized clinical trials to improve their management.

Sites: London Health Sciences Centre The Ottawa Hospital

Tags: Early stage Breast Cancer Survey


  • Developing Patient-Centered Strategies to Optimize the Management of Vasomotor Symptoms in Breast Cancer Patients: A Survey of Health Care Providers. Cole et al, 2021. PMID: 34159473
  • Using machine learning to predict individual patient toxicities from cancer treatments. Cole et al, 2022. PMID: 35614153